The Molecular and Cellular Mechanobiology laboratory is located between LENS (European Laboratory for Non-linear Spectroscopy) and the Department of Physics of the University of Florence, Italy. Our research lies across physics and biology. On one hand, we investigate the physics of biological systems and develop techniques for the study of biology at the molecular scale, with a particular interest on optical methods. On the other hand, we are particularly interested in the molecular mechanisms underlying mechanical regulation of biological systems. Our biological interests encompass the study of the chemomechanical properties of molecular motors and transcription factors and, more in general, biomolecular interactions; the molecular mechanisms of mechanotransduction; and the conversion of mechanical signals into changes in gene expression and cell fate.